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Accelerating the Pace of Substance Use Research Using Existing Data (R21 Clinical Trial Not Allowed)

National Institutes of Health · Opportunity RFA-DA-26-056

Deadline December 3, 2027 450 days left
Award range Not stated
Total program funding
PostedDecember 5, 2024

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

About this opportunity

The purpose of this notice of funding opportunity (NOFO) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors (defined as alcohol, tobacco, prescription and other drug) and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV.

Award history — this exact opportunity

NIH RePORTER lists 3 funded awards under RFA-DA-26-056 across 3 organizations.

Awards by fiscal year 2026: 3
Award size (min / median / max) $208k / $422k / $477k

Total award obligations, not per-year amounts.

Recent awardees include: UNIVERSITY OF NEBRASKA MEDICAL CENTER, MASSACHUSETTS GENERAL HOSPITAL, HENRY M. JACKSON FDN FOR THE ADV MIL/MED.

Source: NIH RePORTER, matched on the exact opportunity number. NIH publishes success rates by institute and activity code — source.

Portfolio context — this listing covers more than this opportunity

This opportunity is funded under Assistance Listing 93.273 (“Alcohol Research Programs”), a broad federal program that made about 265 new awards per year over the last five fiscal years (median award $430k). Those figures describe that whole portfolio — not this specific solicitation, so we don't show them as if they were this opportunity's track record.

Applicant counts per solicitation are not published by any federal agency — no one can honestly sell you that number. NIH publishes success rates by institute and activity code — source.

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