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NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Required)

National Institutes of Health · Opportunity PAR-23-287

Deadline October 14, 2026 35 days left
Award range Not stated
Total program funding
PostedNovember 8, 2023

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

About this opportunity

The purpose of the NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00) program is to increase and maintain a strong cohort of new and talented, NCI-supported, independent investigators. This program is designed for postdoctoral fellows with research and/or clinical doctoral degrees who do not require an extended period of mentored research training beyond their doctoral degrees. The objective of this award is to facilitate a timely transition of these fellows from their mentored, postdoctoral research positions to independent tenure-track (or equivalent) faculty positions. The program will provide independent NCI research support during this transition to help awardees to launch competitive, independent research careers. Researchers in the scientific areas of cancer control, cancer prevention and cancer data sciences are especially encouraged to work with their institutions to apply. This notice of funding opportunity (NOFO) is designed specifically for candidates proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Those not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion NOFO (PAR-23-286).

Award history — this exact opportunity

NIH RePORTER lists 12 funded awards under PAR-23-287 across 9 organizations.

Awards by fiscal year 2025: 5 · 2026: 7
Award size (min / median / max) $70k / $141k / $249k

Total award obligations, not per-year amounts.

Recent awardees include: FRED HUTCHINSON CANCER CENTER, INDIANA UNIVERSITY INDIANAPOLIS, WAKE FOREST UNIVERSITY HEALTH SCIENCES, DANA-FARBER CANCER INST, MASSACHUSETTS GENERAL HOSPITAL, HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH, UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH, UNIVERSITY OF PITTSBURGH AT PITTSBURGH.

Source: NIH RePORTER, matched on the exact opportunity number. NIH publishes success rates by institute and activity code — source.

Portfolio context — this listing covers more than this opportunity

This opportunity is funded under Assistance Listing 93.398 (“Cancer Research Manpower”), a broad federal program that made about 371 new awards per year over the last five fiscal years (median award $122k). Those figures describe that whole portfolio — not this specific solicitation, so we don't show them as if they were this opportunity's track record.

Applicant counts per solicitation are not published by any federal agency — no one can honestly sell you that number. NIH publishes success rates by institute and activity code — source.

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