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Cancer Prevention and Control Clinical Trials Grant Program (R01 Clinical Trial Required)

National Institutes of Health · Opportunity PAR-25-167

Deadline January 7, 2027 120 days left
Award range Not stated
Total program funding
PostedNovember 12, 2024

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

About this opportunity

Through this notice of funding opportunity (NOFO), the National Cancer Institute (NCI) invites applications for support of investigator-initiated clinical trials that have the potential to reduce the burden of cancer through improvements in early detection, screening, prevention and interception, healthcare delivery, quality of life, and/or survivorship related to cancer; with such attributes, the proposed studies should also have the potential to improve clinical practice and/or public health. Applications submitted to this NOFO must include studies that meet the National Institutes of Health (NIH) definition of a clinical trial (see NOT-OD-15-015 for details) and provide specific clinical trial information as described in this FOA. This NOFO does not and will not support clinical trials for studies of cancer diagnosis and/or oncologic therapy in patients. The proposed investigator-initiated projects should be related to the programmatic interests of the NCI Division of Cancer Prevention and/or the NCI Division of Cancer Control and Population Sciences.

Award history — this exact opportunity

NIH RePORTER lists 46 funded awards under PAR-25-167 across 38 organizations.

Awards by fiscal year 2026: 46
Award size (min / median / max) $282k / $659k / $2.2M

Total award obligations, not per-year amounts.

Recent awardees include: SLOAN-KETTERING INST CAN RESEARCH, UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR, UNIVERSITY OF MICHIGAN AT ANN ARBOR, RUTGERS BIOMEDICAL AND HEALTH SCIENCES, UNIVERSITY OF CALIFORNIA LOS ANGELES, NORTHWESTERN UNIVERSITY, BRIGHAM AND WOMEN'S HOSPITAL, ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI.

Source: NIH RePORTER, matched on the exact opportunity number. NIH publishes success rates by institute and activity code — source.

Portfolio context — this listing covers more than this opportunity

This opportunity is funded under Assistance Listing 93.393 (“Cancer Cause and Prevention Research”), a broad federal program that made about 318 new awards per year over the last five fiscal years (median award $1.1M). Those figures describe that whole portfolio — not this specific solicitation, so we don't show them as if they were this opportunity's track record.

Applicant counts per solicitation are not published by any federal agency — no one can honestly sell you that number. NIH publishes success rates by institute and activity code — source.

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