← All grants

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

National Institutes of Health · Opportunity PA-27-100

Deadline April 5, 2027 208 days left
Award range Not stated
Total program funding
PostedMay 28, 2026

Who can apply

Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity.Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Unfunded international collaborations or unfunded foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

About this opportunity

The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.

Award history — Chronic Diseases: Research, Control, and Prevention (Assistance Listing 93.068)

This program made 8 new awards in FY2025.

New awards by fiscal year ’21: 5 · ’22: 15 · ’23: 23 · ’24: 29 · ’25: 8
Award size (min / median / max) $73k / $1.2M / $27.3M

Across the 80 most recent awards. Total obligations, not per-year.

Repeat winners 7 of 73 recipients won more than once

New awards recorded on USAspending.gov under the federal program that funds this opportunity. FY2025 figures may still be incomplete. Per-solicitation applicant counts are not published, so a true success rate for this specific opportunity cannot be computed. NIH publishes success rates by institute and activity code — source.

Apply on grants.gov →

Don't want to hunt for grants like this one? Get free deadline alerts for your state and focus areas.

Consultant or grant writer? See the client-ready Opportunity Brief for this grant — actual award sizes vs. the advertised ceiling, who wins, printable "prepared for your client" version.

Similar grants still open

OpportunityAgencyDeadlineAward ceilingEligible
NIH Director’s Pioneer Award (DP1 Clinical Trial Optional) National Institutes of Health September 9, 2026 0d left $700k Nonprofits
Fiscal Year 2027 Expanding Nutrition Services Health Resources and Services Administration September 9, 2026 0d left $350k
NIH Director’s Early Independence Award (DP5 Clinical Trial Optional) National Institutes of Health September 10, 2026 1d left $350k Nonprofits
Improving the Capacity of Tribal Communities to Identify Emerging Drug Threats Office of National Drug Control Policy September 13, 2026 4d left $300k Nonprofits