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Limited Competition: Superfund Hazardous Substance Research and Training Program (P42 Clinical Trial Optional)

National Institutes of Health · Opportunity RFA-ES-27-004

Deadline September 25, 2028 747 days left
Award range Up to $1.8M
Total program funding $22M

≈ 10 awards expected

PostedMay 19, 2026

Who can apply

Based on 42 USC 9660(a)(3) eligible applicants are limited to accredited institutes of higher education. Eligible applicants are permitted under the law, and encouraged by NIEHS, to subcontract as appropriate with other organizations as necessary to conduct portions of the research. Examples of other organizations may include generators of hazardous wastes; persons involved in the detection, assessment, evaluation, and treatment of hazardous substances; owners and operators of facilities at which hazardous substances are located; and/or State and local governments. Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

About this opportunity

The National Institute of Environmental Health Sciences (NIEHS) is announcing the continuation of the Superfund Hazardous Substance Research and Training Program, referred to as Superfund Research Program (SRP) Centers. SRP Center grants will support problem-based, solution-oriented research Centers that consist of multiple, integrated projects representing both the biomedical and environmental science and engineering disciplines; as well as cores tasked with administrative (which includes Center leadership, data management, and training); translational research and engagement; and research support functions. The scope of the SRP Centers is taken directly from the Superfund Amendments and Reauthorization Act of 1986, which limits competition for this program to accredited institutes of higher education.Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Award history — NIEHS Superfund Hazardous Substances_Basic Research and Education (Assistance Listing 93.143)

This program made 4 new awards in FY2025.

New awards by fiscal year ’21: 25 · ’22: 13 · ’23: 7 · ’24: 12 · ’25: 4
Award size (min / median / max) $15k / $433k / $11.4M

Across the 61 most recent awards. Total obligations, not per-year.

Repeat winners 7 of 49 recipients won more than once

New awards recorded on USAspending.gov under the federal program that funds this opportunity. FY2025 figures may still be incomplete. Per-solicitation applicant counts are not published, so a true success rate for this specific opportunity cannot be computed. NIH publishes success rates by institute and activity code — source.

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