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NIH Research Project Grant (Parent R01 Clinical Trial Required)

National Institutes of Health · Opportunity PA-25-305

Deadline January 7, 2028 485 days left
Award range Not stated
Total program funding
PostedDecember 18, 2024

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

About this opportunity

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). This Parent Notice of Funding Opportunity Announcement requires that at lease 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

Award history — this exact opportunity

NIH RePORTER lists 205 funded awards under PA-25-305 across 99 organizations.

Awards by fiscal year 2025: 1 · 2026: 204
Award size (min / median / max) $110k / $731k / $2M

Total award obligations, not per-year amounts.

Recent awardees include: UNIVERSITY OF MICHIGAN AT ANN ARBOR, UNIVERSITY OF VIRGINIA, JOHNS HOPKINS UNIVERSITY, UNIVERSITY OF CALIFORNIA LOS ANGELES, UNIVERSITY OF COLORADO DENVER, STATE UNIVERSITY OF NEW YORK AT BUFFALO, MAYO CLINIC ROCHESTER, NEW YORK UNIVERSITY SCHOOL OF MEDICINE.

Source: NIH RePORTER, matched on the exact opportunity number. NIH publishes success rates by institute and activity code — source.

Portfolio context — this listing covers more than this opportunity

This opportunity is funded under Assistance Listing 93.113 (“Environmental Health”), a broad federal program that made about 246 new awards per year over the last five fiscal years (median award $468k). Those figures describe that whole portfolio — not this specific solicitation, so we don't show them as if they were this opportunity's track record.

Applicant counts per solicitation are not published by any federal agency — no one can honestly sell you that number. NIH publishes success rates by institute and activity code — source.

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