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NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)

National Institutes of Health · Opportunity PA-25-301

Deadline January 7, 2028 485 days left
Award range Not stated
Total program funding
PostedDecember 18, 2024

Who can apply

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

About this opportunity

The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s). The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.This Notice of Funding Opportunity does not accept applications proposing clinical trial(s).

Award history — this exact opportunity

NIH RePORTER lists 3146 funded awards under PA-25-301 across 156 organizations.

Awards by fiscal year 2025: 2 · 2026: 498
Award size (min / median / max) $1.0 / $668k / $3.8M

Total award obligations, not per-year amounts.

Recent awardees include: UNIVERSITY OF PENNSYLVANIA, STANFORD UNIVERSITY, DUKE UNIVERSITY, JOHNS HOPKINS UNIVERSITY, UNIVERSITY OF CALIFORNIA, SAN FRANCISCO, COLUMBIA UNIVERSITY HEALTH SCIENCES, ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, UNIVERSITY OF MICHIGAN AT ANN ARBOR.

Source: NIH RePORTER, matched on the exact opportunity number. NIH publishes success rates by institute and activity code — source.

Portfolio context — this listing covers more than this opportunity

This opportunity is funded under Assistance Listing 93.113 (“Environmental Health”), a broad federal program that made about 246 new awards per year over the last five fiscal years (median award $468k). Those figures describe that whole portfolio — not this specific solicitation, so we don't show them as if they were this opportunity's track record.

Applicant counts per solicitation are not published by any federal agency — no one can honestly sell you that number. NIH publishes success rates by institute and activity code — source.

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