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Limited Competition: Specific Pathogen Free Macaque Colonies to Support HIV/AIDS Research (U42 Clinical Trial Not Allowed)

National Institutes of Health · Opportunity PAR-24-129

Deadline September 25, 2026 16 days left
Award range Not stated
Total program funding
PostedJanuary 22, 2024

Who can apply

Other Eligible Applicants include the following:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. see NOFO for eligibility details

About this opportunity

The purpose of this Notice of Funding Opportunity (NOFO) is to provide continuing support for specific pathogen-free (SPF) macaque colonies previously funded under the auspices of PAR-21-089 and PAR-18-669 that support Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) research. Breeding colonies are essential to sustain appropriate SPF macaques for research related to HIV/AIDS. Pedigree SPF macaques are free of certain viruses, which may confound the results of HIV/AIDS-related investigations or present a risk to the personnel who care for the animals. The SPF macaques are genetically characterized for major histocompatibility complex (MHC) class I types, because MHC class I genotypes have large effects on macaque immune responses to Simian Immunodeficiency Virus (SIV) that can induce AIDS in nonhuman primates (NHPs) and on human immune responses to HIV.

Award history — this exact opportunity

NIH RePORTER lists 32 funded awards under PAR-24-129 across 4 organizations.

Awards by fiscal year 2024: 4 · 2025: 12 · 2026: 16
Award size (min / median / max) $30k / $729k / $2.3M

Total award obligations, not per-year amounts.

Recent awardees include: TULANE UNIVERSITY OF LOUISIANA, OREGON HEALTH & SCIENCE UNIVERSITY, EMORY UNIVERSITY, JOHNS HOPKINS UNIVERSITY.

Source: NIH RePORTER, matched on the exact opportunity number. NIH publishes success rates by institute and activity code — source.

Portfolio context — this listing covers more than this opportunity

This opportunity is funded under Assistance Listing 93.310 (“Trans-NIH Research Support”), a broad federal program that made about 574 new awards per year over the last five fiscal years (median award $981k). Those figures describe that whole portfolio — not this specific solicitation, so we don't show them as if they were this opportunity's track record.

Applicant counts per solicitation are not published by any federal agency — no one can honestly sell you that number. NIH publishes success rates by institute and activity code — source.

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