Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)

National Institutes of Health · RFA-OD-25-010 · Deadline: September 28, 2028

Program-level history — this opportunity doesn't publish per-opportunity awards, so these numbers describe its parent program (CFDA 93.351, Research Infrastructure Programs), not this competition alone. Labeled that way on purpose.

Program volume ~188 awards/yr

205 unique recipients in the sample; 96 repeat winners.

Actual award size (program) $578k median

range $5k – $6.3M

Draw-down reality (program)

Across 377 completed awards in this program (FY2021+ sample, USAspending outlay records), grantees ultimately drew a median 100% of obligated funds. A median well under 100% means underspend or early closure is common here — worth knowing before promising a spend-down timeline.

Listing summary

The Office of Research Infrastructure Programs (ORIP) encourages grant applications aimed at developing, characterizing, or improving research models of human health and diseases; developing biology based new approach methodologies (NAMs) applicable to human health and diseases; or improving access to information about or generated from the use of models of human disease. The models, including NAMs, and related biological materials developed must be broadly applicable to the scientific interests of two or more NIH Institutes or Centers (ICs) and must evaluate diseases and processes that impact…

Eligibility: State governments, County governments, City or township governments, Public and State institutions of higher education, Native American tribal governments (Federally recognized), Nonprofits with 501(c)(3), other than higher education, Nonprofits without 501(c)(3), Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others · Categories: Health · official listing ↗

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Sources: NIH RePORTER (opportunity-exact) and USAspending (program-level), labeled per section. GrantsDue computes summaries only; verify anything critical against the originals. Methodology.