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Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

National Institutes of Health · PAR-25-378 · Deadline: January 7, 2027

Program-level history — this opportunity doesn't publish per-opportunity awards, so these numbers describe its parent program (CFDA 93.113, Environmental Health), not this competition alone. Labeled that way on purpose.

Program volume ~246 awards/yr

195 unique recipients in the sample; 83 repeat winners.

Actual award size (program) $468k median

range $2k – $32.8M

Draw-down reality (program)

Across 128 completed awards in this program (FY2021+ sample, USAspending outlay records), grantees ultimately drew a median 92% of obligated funds. A median well under 100% means underspend or early closure is common here — worth knowing before promising a spend-down timeline.

Listing summary

The purpose of this notice of funding opportunity (NOFO) is to support research on interventions to improve health in Native American (NA) populations. This includes 1) etiologic research, where there is a significant gap in knowledge, that will directly inform intervention development or adaptations, 2) research that develops, adapts, or tests the efficacy or effectiveness of health promotion and disease prevention interventions, 3) research that tests culturally informed treatment or recovery interventions and 4) where a sufficient body of knowledge on intervention efficacy exists, research …

Eligibility: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities, Native American tribal organizations (other), Nonprofits with 501(c)(3), other than higher education, Nonprofits without 501(c)(3), Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others · Categories: Education, Environment, Health, Income Security and Social Services · official listing ↗

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Sources: NIH RePORTER (opportunity-exact) and USAspending (program-level), labeled per section. GrantsDue computes summaries only; verify anything critical against the originals. Methodology.