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Assay Development for High Throughput Molecular Screening (R21)

National Institutes of Health · Opportunity PAR-08-024

Who can apply

• State governments
• County governments
• City or township governments
• Special district governments
• Independent school districts
• Public and State institutions of higher education
• Native American tribal governments (Federally recognized)
• Public housing authorities
• Native American tribal organizations (other)
• Nonprofits with 501(c)(3), other than higher education
• Nonprofits without 501(c)(3)
• Private institutions of higher education
• For-profit organizations other than small businesses
• Small businesses
• Others

Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith-based or community-based organizations can apply.

About this opportunity

-Purpose. This PAR will facilitate the discovery of new molecular probes for investigating biological function by funding the development and adaptation of biological assays for use in automated High-Throughput Screening (HTS) projects. These HTS-ready assays can then be screened by the Molecular Libraries Production Centers Network (MLPCN) to identify biologically active compounds in a large library of small molecule chemical structures. This Program and the MLPCN are both components of the NIH Molecular Libraries and Imaging Roadmap Initiative (http://nihroadmap.nih.gov/molecularlibraries/index.asp). -Mechanism of Support. This Funding Opportunity Announcement (FOA) will utilize the R21 grant mechanism. -Funds Available and Anticipated Number of Awards. Approximately $8 million will be available for this PAR in 2008, 2009 and 2010. This amount will be distributed in response to two receipt dates per year. NIH anticipates making approximately 40 awards in total each year. Because the scope of the proposed research will vary from application to application, it is anticipated that the size of each award will also vary. The total amount awarded and the number of awards will depend upon the quality and costs of the applications received.

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